ASEE ADMISSION-CUM-SCHOLARSHIP ENTRANCE EXAMINATION http://QuestionPaper.in/EntranceExam88-ASEE.aspx ASEE ADMISSION-CUM-SCHOLARSHIP ENTRANCE EXAMINATION en-us About ASEE http://QuestionPaper.in/EntranceExam88-ASEE.aspx#About-ASEE Scheme of Examination http://QuestionPaper.in/EntranceExam88-ASEE.aspx#Scheme-of-Examination Candidate is expected to choose the most correct/ best suitable answer.]]> Scoring and Negative Marking http://QuestionPaper.in/EntranceExam88-ASEE.aspx#Scoring-and-Negative-Marking Eligibility http://QuestionPaper.in/EntranceExam88-ASEE.aspx#Eligibility M.Sc. Biotechnology
B.Sc. Biotech/CBZ or equivalent with >=55% marks

M.Sc. Pharmaceutical Chemistry
B.Sc. CBZ/ PCM or equivalent with >=50% marks

M.Sc. Microbiology
B.Sc. Microbiology/CBZ or equivalent with >=50% marks

B.Sc. Biotechnology (with CBZ)
10+2 with PCB with >=45% marks in aggregate
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M.Sc. Microbiology Syllabus http://QuestionPaper.in/EntranceExam88-ASEE.aspx#MSc-Microbiology-Syllabus Taxonomic aids, keys, specimen management; Systematics & binomial system of nomenclature; Classification of living organisms (5 kingdom system, major  groups and principles of classification within each group); General description & Salient features of Monerans, Protists, Fungi, Plants and Animals (with major groups).

2. Biochemistry (8 Questions)
Entropy, Enthalpy; Gibb’s free energy concept; Laws of thermodynamics; Acids & bases; pH & buffers; Structure, function & metabolism of carbohydrates,  proteins, lipids and nucleic acids; Enzymology: Classification and nomenclature of enzymes; Structure, Mechanism of action, single substrate and bi-substrate  enzymes; Activators and inhibitors of enzymes; Factors affecting the activity of enzymes.

3. Plant Physiology (8 Questions)
Minerals required by plant, their absorbable form, functions, deficiency symptoms, essentiality of minerals, N2 metabolism, biological N2 fixation; Cellular  Metabolism: Gluconeogenesis, Glycogenesis and glycogenolysis, hormonal regulation; Oxidation of food, respiratory efficiency of various food components;  transport and detoxification of ammonia, Lipid Metabolism; Photosynthesis: Basic principles of light absorption, excitation energy transfer, electron transports, cycles (C2, C3, C4 & CAM), plant productivity, measurement of photosynthetic parameters; Physiological responses to abiotic stresses; Sensory  photobiology; Physiological affects and mechanism of action of plant growth hormones.

4. Human Biology (8 Questions)
General Morphology & Anatomy; Physiology: Control and Disorders of Digestion, Respiration, Body fluids and Circulation, Homoeostasis, Excretion & Urea cycle, Skeleton system & muscle contraction, Nervous system; Immunobiology.

5. Classical Genetics (8 Questions)
Principles of Inheritance and Variation: Mendelian genetics, Post Mendelian inheritance; chromosomal theory of inheritance; Linkage, recombination & crossing over; recombination frequency, linkage map; Mutation: General properties of mutations; molecular basis of gene mutation: biochemical basis of gene  mutation DNA repair mechanisms. Pedigree analysis; Human karyotype-banding; genetic and environmental basis of sex determination, Y- and X-linked  genes, Numerical and Structural abnormalities of human chromosomes and related syndromes: Human metabolic disorders; Maternal inheritance; Molecular  Basis of Inheritance: Chemical nature of DNA and RNA; Biological functions of nucleic acids; Search for genetic material, RNA world; Replication; Transcription and processing of RNA, Genetic code; Translation, posttranslational modification; Ribosomes; Regulation of Gene expression.

6. Cell & Molecular Biology (10 Questions)
History of cell biology; Microscopy; Staining technique; Centrifugation; Radio-labeling techniques (RIA); Immuno-blotting; ELISA; Study of cytoplasm &  plasma membrane; Structure & Function of Cell-organelles; Genes & Genome; C-value paradox; DNA packaging: Nucleosome model; DNA super-coiling;  DNA Replication, recombination & repair; Transcription & RNA splicing; Translation of protein & gene regulation.

7. Modern Genetics (10 Questions)
Gel Electrophoresis (Agarose/ PAGE/ SDS-PAGE/ Pulse-Field GE); Southern blotting, Northern blotting & Western Blotting; DNA Fingerprinting; Gene  mapping; Chromosome banding; Genetics in modern agriculture, animal breeding, medicine, human behavior; Genetic Counseling; Gene therapy; HGP; Gene  Activity in prokaryotes and eukaryotes; Signals for gene control – Hormones and growth factors; Bacterial transformation, transduction and conjugation,  Bacterial chromosome; Bacteriophages: Types, structure and morphology.

8. Evolutionary Biology (8 Questions)
Cosmic evolution – Physical basis of life; Theories of origin of life; Origin of life through biochemical evolution; Experimental evidences for origin of life;  Evolution of the prokaryotic & eukaryotic cell; Direct & indirect evidences of evolution (specially study of fossils); Theories of organic evolution- Lamarckism  & Darwinism; Speciation & variation; Origin and evolution of horse & man; Population Genetics; Genetic variations; Polymorphism; Gene  frequency; Hardy Weinberg equilibrium; Genetic drift, Founder effect; Adaptive radiation; ecological significance of molecular variations.

9. Ecology (10 Questions)
Ecology: definition, study, branches; Concept of ecosystem; Organism and its environment, distribution of biomes, major physical factors and the  physiological responses shown by organisms; Physical adaptation of plants and animals, rules governing adaptations; Population attributes and growth, logistic  curves, Darwinian fitness; Population interactions and their theories; Ecosystem structure and functions, ecosystem productivity and standing crop, decomposition in nature, energy flow in ecosystem, ecological pyramids, succession of community; Biogeochemical cycles; Biodiversity types and its patterns, importance of diversity, its loss and their causes, conservation strategies ; Environmental issues : Types of pollution, their indicators, causes, effects, prevention and treatment ; Deforestation, recommended forestation, reforestation, case, Chipko Movement; Ozone layer depletion; Global warming; Green
house effect.

10. Biostatistics (5 Questions)
General mathematical ability, Measures of central tendency (mean median & mode), standard deviation, variance & standard error, chi-square test.

11. Biology and Human Welfare (10 Questions)
Health and disease; types of diseases, common diseases in humans; Immunology – Innate and Acquired immunity; Passive and active immunization;  Organization and structure of lymphoid organ; Cells of the immune system; Nature of immune response; Structure and Functions of antibodies: Antigen-Antibody interactions; Humoral immune response; Cell mediated immunity; Auto-immunity; Allergies; Immunodeficiency disorders; etiology of HIV; types, genetics and biochemistry of cancer; Animal husbandry, management of farm animals, breeding strategies (natural and artificial) and their types, economic importance of each; Plant breeding, method of release of new variety, Single cell protein; Tissue culture technique, somatic hybridization; Microbes in Human Welfare: Technology associated and use of Microbes in household, industries, medicine, bio-active molecules, sewage treatment and sewage treatment plants, biogas production, bio-control agents, biofertilizers.

12. Microbiology & Biotechnology (10 Questions)
Microbial Culture technique; microbial tools; Isolation, media preparation, cultivation, staining & preservation of microbes; Application of microbiology in  dairy, agriculture, medicine and environmental engineering; technique of separation and isolation of DNA, RNA & Protein; Cryopreservation; Gene cloning, Restriction enzymes, Isoschizomers & Isocaudomers; Cutting & Joining of Nucleic acids, linkers & adapters; Vectors (plasmid/ viral & phage vectors/  cosmid/ fosmid/ BAC/ YAC/ HAC), types of vectors (cloning & expression vectors/ shuttle vectors), vectors for plants (Ti plasmid & Ri plasmid); genomic  and cDNA libraries; nucleotide sequence comparisons and homologies; RFLP, SNP, VNTR, STR, RAPD; general description, types & application of PCR;  io-reactors, upstream & downstream processing, large scale production; Totipotency & Pleuripotency; stem cell technology; Tissue engineering;  Hybridoma technique: production, detection and applications of monoclonal antibodies; Study of vaccines: mechanism of vaccination; types of vaccines; OPV, Hepa]]>
M.Sc. Biotechnology Syllabus http://QuestionPaper.in/EntranceExam88-ASEE.aspx#MSc-Biotechnology-Syllabus Taxonomic aids, keys, specimen management; Systematics & binomial system of nomenclature; Classification of living organisms (5 kingdom system, major  groups and principles of classification within each group); General description & Salient features of Monerans, Protists, Fungi, Plants and Animals (with major groups).

2. Biochemistry (8 Questions)
Entropy, Enthalpy; Gibb’s free energy concept; Laws of thermodynamics; Acids & bases; pH & buffers; Structure, function & metabolism of carbohydrates,  proteins, lipids and nucleic acids; Enzymology: Classification and nomenclature of enzymes; Structure, Mechanism of action, single substrate and bi-substrate enzymes; Activators and inhibitors of enzymes; Factors affecting the activity of enzymes.

3. Plant Physiology (8 Questions)
Water relations: Properties of water, water in tissues and cells, Transport of water and solutes (food, nutrients, gases): Transport across cell membrane;  soil-plant-atmosphere continuum; Minerals required by plant, their absorbable form, functions, deficiency symptoms, essentiality of minerals, N2 metabolism, biological N2 fixation; Cellular Metabolism: Gluconeogenesis, Glycogenesis and glycogenolysis, hormonal regulation; Oxidation of food, respiratory efficiency of various food components; transport and detoxification of ammonia, Lipid Metabolism; Photosynthesis: Basic principles of light absorption, excitation  energy transfer, electron transports, cycles (C2, C3, C4 & CAM), plant productivity, measurement of photosynthetic parameters; Physiological responses to abiotic stresses; Sensory photobiology; Physiological affects and mechanism of action of plant growth hormones; Photoperiodism and its significance,  ndogenous clock and its regulation, floral induction and development, Vernalization; Plant movements; Seed dormancy.

4. Human Biology (8 Questions)
General Morphology & Anatomy; Physiology: Control and Disorders of Digestion, Respiration, Body fluids and Circulation, Homoeostasis, Excretion &  Urea cycle, Skeleton system & muscle contraction, Nervous system; Immunobiology.

5. Classical Genetics (8 Questions)
Principles of Inheritance and Variation: Mendelian genetics, Post Mendelian inheritance; chromosomal theory of inheritance; Linkage, recombination &  crossing over; recombination frequency, linkage map; Mutation: General properties of mutations; molecular basis of gene mutation: biochemical basis of gene  mutation DNA repair mechanisms. Pedigree analysis; Human karyotype-banding; genetic and environmental basis of sex determination, Y- and X-linked  genes, Numerical and Structural abnormalities of human chromosomes and related syndromes: Human metabolic disorders; Maternal inheritance; Molecular Basis of Inheritance: Chemical nature of DNA and RNA; Biological functions of nucleic acids; Search for genetic material, RNA world; Replication; Transcription and processing of RNA, Genetic code; Translation, posttranslational modification; Ribosomes; Regulation of Gene expression.

6. Cell & Molecular Biology (10 Questions)
History of cell biology; Microscopy; Staining technique; Centrifugation; Radio-labeling techniques (RIA); Immuno-blotting; ELISA; Study of cytoplasm &  plasma membrane; Structure & Function of Cell-organelles; Genes & Genome; C-value paradox; DNA packaging: Nucleosome model; DNA super-coiling;  DNA Replication, recombination & repair; Transcription & RNA splicing; Translation of protein & gene regulation.

7. Modern Genetics (10 Questions)
Gel Electrophoresis (Agarose/ PAGE/ SDS-PAGE/ Pulse-Field GE); Southern blotting, Northern blotting & Western Blotting; DNA Fingerprinting; Gene  mapping; Chromosome banding; Genetics in modern agriculture, animal breeding, medicine, human behavior; Genetic Counseling; Gene therapy; HGP; Gene Activity in prokaryotes and eukaryotes; Signals for gene control – Hormones and growth factors; Bacterial transformation, transduction and conjugation, Bacterial chromosome; Bacteriophages: Types, structure and morphology.

8. Evolutionary Biology (8 Questions)
Cosmic evolution – Physical basis of life; Theories of origin of life; Origin of life through biochemical evolution; Experimental evidences for origin of life;  Evolution of the prokaryotic & eukaryotic cell; Direct & indirect evidences of evolution (specially study of fossils); Theories of organic evolution- Lamarckism  & Darwinism; Speciation & variation; Origin and evolution of horse & man; Population Genetics; Genetic variations; Polymorphism; Gene frequency; Hardy Weinberg equilibrium; Genetic drift, Founder effect; Adaptive radiation; ecological significance of molecular variations.

9. Ecology (10 Questions)
Ecology: definition, study, branches; Concept of ecosystem; Organism and its environment, distribution of biomes, major physical factors and the  physiological responses shown by organisms; Physical adaptation of plants and animals, rules governing adaptations; Population attributes and growth, logistic  urves, Darwinian fitness; Population interactions and their theories; Ecosystem structure and functions, ecosystem productivity and standing crop,  decomposition in nature, energy flow in ecosystem, ecological pyramids, succession of community; Biogeochemical cycles; Biodiversity types and its patterns,  importance of diversity, its loss and their causes, conservation strategies ; Environmental issues : Types of pollution, their indicators, causes, effects,  prevention and treatment ; Deforestation, recommended forestation, reforestation, case, Chipko Movement; Ozone layer depletion; Global warming; Green house effect.

10. Biostatistics (5 Questions)
General mathematical ability, Measures of central tendency (mean median & mode), standard deviation, variance & standard error, chi-square test.

11. Biology and Human Welfare (10 Questions)
Health and disease; types of diseases, common diseases in humans; Immunology – Innate and Acquired immunity; Passive and active immunization;  Organization and structure of lymphoid organ; Cells of the immune system and their differentiation; Lymphocyte traffic; Nature of immune response; Structure and Functions of antibodies: Antigen- Antibody interactions; Humoral immune response; Cell mediated immunity; Immunological memory; Auto-immunity;  Allergies; HLA system in human: MHC haplotypes; Transplantation types and problems; Immunodeficiency disorders; etiology of HIV; types, genetics and  biochemistry of cancer; Drugs and alcohol abuse, Addiction, drug dependence, ill effects, prevention, its abuse in adolescents and its management; Strategies  for food production and enhancement: Animal husbandry, management of farm animals, breeding strategies (natural and artificial) and their types, economic importance of each; Plant breeding, method of release of new variety, Single cell protein; Tissue culture technique, somatic hybridization; Microbes in Human  Welfare: Technology associated and use of Microbes in household, industries, medicine, bio-active molecules, sewage treatment and sewage treatment  plants, biogas production, bio-control agents, biofertilizers.

12. Biotechnology & Genetic Engineering (10 Questions)
Genetic engineering tools & technique; Technique of separation and isolation of DNA, RNA & Protein; Cryopreservation; Gene cloning, restriction enzymes,  soschizomers & isocaudomers; Cutting & joining of nucleic acids, linkers & adapters; Vectors (plasmid/ viral & phage vectors/ cosmid/ fosmid/  phasmid/ BAC/ YAC/ HAC), types of vectors (cloning & expression vectors/ shuttle vectors), vectors for plants ]]>
M.Sc. Pharmaceutical Chemistry Syllabus http://QuestionPaper.in/EntranceExam88-ASEE.aspx#MSc-Pharmaceutical-Chemistry-Syllabus Atomic Structure; Periodic table & periodic properties; Chemical bonding; s-block elements; p-block elements; d-block elements & coordination  compounds; chemistry of noble gases; Oxidation & reduction; Organo-metallic compounds Hybridization; Mechanism of organic reaction; Stereochemistry  of organic compounds; Isolation, purification, identification & classification of organic compounds; Isomerism; Hydrocarbons (aliphatic & aromatic);  Alcohols; Phenols; Ethers & Epoxides; Aldehyde & ketones; Carboxylic Acids; Structure & Function of Bio-molecules (Carbohydrate, Proteins & Amino- acids, Nucleic Acids, Vitamins); Organic compounds of Nitrogen. Chemical equilibrium & chemical kinetics; Gaseous state; Liquid state; Solid state; Colloidal system; Catalysts & catalysis; Solution; Distribution law; Thermodynamics; Entropy, Enthalpy; Gibb’s free energy concept; Acids & bases; pH &  buffers; Electrochemistry; Phase equilibrium; Surface Chemistry.

2. Tools & Techniques in Pharmaceutics (10 Questions) [Compulsory for All]
Disease Diagnosis techniques (including ELISA & PCR), Centrifugation and ultra centrifugation, gel permeation; Ion exchange chromatography,  electrophoresis, hydrophobic interaction, partition chromatography; Colorimetry, UV-visible spectrophotometry, fluorescence spectroscopy, x-ray  crystallography, radio isotopes techniques; Salt precipitation, precipitation with organic solvent; Microscopy- LM,TEM,SEM; Cell fractionation, cell growth  determination; Chromosomal techniques- Staining , banding pattern, karyotyping; Mutagenic techniques- Bacterial and seed mutagenesis , recombination in bacteria, conjugation, transduction, breeding methods in plants, pedigree analysis, DNA isolation.

3. Biology (30 Questions) [For BIO Group: PCB]
Microbial culture tools & techniques; Isolation, media preparation, cultivation, staining & preservation of microbes; Application of microbiology in dairy,  agriculture, medicine and environmental engineering; History of cell biology; Microscopy; Staining technique; Centrifugation; Study of cytoplasm & plasma membrane; Structure & Function of Cell-organelles; Genes & Genome; DNA Replication; Transcription; Translation of protein & gene regulation. Principles of Inheritance and Variation: Mendelian genetics, Post Mendelian inheritance; chromosomal theory of inheritance; Linkage, recombination & crossing over; recombination frequency; Mutation; Numerical and Structural abnormalities of human chromosomes and related syndromes. Chemical nature of DNA and  RNA; Biological functions of nucleic acids; Search for genetic material, RNA world; Replication; Transcription and processing of RNA, Genetic code;  Translation, post-translational modification; Ribosomes; Regulation of Gene expression. Structure, function & metabolism of carbohydrates, proteins, lipids  and nucleic acids; Enzymology: Classification and nomenclature of enzymes; Structure, Mechanism of action, single substrate and bi-substrate enzymes;  Activators and inhibitors of enzymes;  Factors affecting the activity of enzymes.Health and disease; types of diseases, common diseases in humans;  Immunology – Innate and Acquired immunity; Passive and active immunization; Organization and structure of lymphoid organ; Cells of the immune system  and their differentiation; Lymphocyte traffic; Nature of immune response; Structure and Functions of antibodies: Antigen- Antibody interactions; Humoral   immune response; Cell mediated immunity; Immunological memory; Auto-immunity; Allergies; Immunodeficiency disorders; HIV; Cancer; Drugs and alcohol  abuse, Addiction, drug dependence, ill effects, prevention, its abuse in adolescents and its management. DNA Fingerprinting; Genetics in modern agriculture,  animal breeding, medicine, human behavior; Gene therapy; bacterial transformation, transduction and conjugation, Bacterial chromosome; Bacteriophages: Types, structure and morphology.

4. Mathematics & Biostatistics (30 Questions) [For Math Group: PCM]
Mensuration (calculation of length, width, height, area, volume etc.); Common algebra; Trigonometry; Mean, median, mode, standard deviation, variation,  standard error; Probability and distribution; Correlation & regression; ANOVA; t-test; Z-test; chi-square test; Integration & Differentiation; Calculus;  Geometry; Equation of Line.
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B.Sc. Biotechnology Syllabus http://QuestionPaper.in/EntranceExam88-ASEE.aspx#BSc-Biotechnology-Syllabus Mensuration (calculation of length, width, height, area, volume etc.); Common algebra; Trigonometry; Time, speed & distance; Geometry; Average,  percentage, profits & loss; Mean, median, mode, standard deviation, variation, standard error & chi-square test.

2. General Mental Ability (3 Questions)
3 questions would be based on general mental ability viz. Simple series completion; Coding-decoding; Analogy.

3. General Awareness (5 Questions):
5 Questions would be based on general awareness regarding science, pollution, population explosion, food crisis, fuel & energy crisis; Current knowledge  concerning the above all.

4. General Chemistry (12 Questions)
Chemical equilibrium & chemical kinetics; Solution; Distribution law; Catalysts & catalysis; Colloidal system; Thermodynamics; Isolation, purification,  identification & classification of organic compounds; Isomerism; Reaction Mechanisms of organic compounds;

5. Biology (60 Questions)
a. Botany (10 Questions)
Questions regarding bacteria, viruses, algae, fungi, bryophytes, pteridophytes, gymnosperms & angiosperms.
b. Zoology (10 Questions)
Questions regarding protozoa, platyhelminthes, annelida, arthropoda & chordata.
c. Genetics (8 Questions)
Mendel’s law, mutation, genetic diseases & syndromes, chromosomal basis of inheritance; incomplete dominance.
d. Cell & Molecular Biology (8 Questions)
Microscopy; Prokaryotic vs. Eukaryotic cell; Study of cell organelles; Nucleus & chromosome; DNA replication, transcription & translation.
e. Biochemistry & Immunology (8 Questions)
Biomolecules (carbohydrate, protein, lipid, nucleic acids, vitamins, hormones etc.), pH & buffer, acid & bases; enzymes; Glycolysis & Kreb’s cycle; Health and disease; types of diseases, common diseases in humans; Immunology – Innate and Acquired immunity; Passive and active immunization.
f. Ecology, Evolution & Environment (8 Questions)
Theories of origin of life; Origin of life through biochemical evolution; Experimental evidences for origin of life; Direct & indirect evidences of evolution  (specially study of fossils); Theories of organic evolution- Lamarckism & Darwinism; Speciation & variation; Origin and evolution of horse & man; Ecology: definition, study, branches; Concept of ecosystem; Organism and its environment; Adaptation of plants and animals, rules governing adaptations; Darwinism; Ecosystem structure and functions, ecosystem productivity and standing crop, decomposition in nature, energy flow in ecosystem, ecological pyramids, succession of community; Biogeochemical cycles; Biological conservation strategies; Environmental issues : Types of pollution, their indicators, causes, effects, prevention and treatment ; Deforestation & reforestation; Chipko Movement; Ozone layer depletion; Global warming; Green house effect.
g. Applied Biology (8 Questions)
Use of microbes, plants & animals for human beings.

6. Introductory Biotechnology (10 Questions)
Genetic engineering tools & technique; Technique of separation and isolation of DNA, RNA & Protein; Cryopreservation; Gene cloning, restriction enzymes;  Cutting & joining of nucleic acids; Vectors (plasmid/ viral & phage vectors), vectors for plants (Ti plasmid & Ri plasmid); Bio-reactors, upstream & downstream processing, large scale production; Totipotency & pleuripotency; Stem cell technology; Tissue engineering; Vaccination: mechanism of  vaccination; types of vaccines; OPV, Hepatitis-B vaccine; Biotechnological products.]]>
Courses http://QuestionPaper.in/EntranceExam88-ASEE.aspx#Courses M.Sc. Pharmaceutical Chemistry
M.Sc. Microbiology
B.Sc. Biotechnology (with CBZ)
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