About ASEE Top The Scholarships are available for all courses. For Post Graduate courses the value of scholarship is Rs. 1 lakh each and for UG course, Rs. 72,000 each.  Students applying for management seats are not eligible for scholarship. Selection will be through a written test. Candidates, meeting the eligibility criteria, will be called for the written test held on 18th, April, 2010. Such successful candidates according to course and seats will be informed by post. If candidates secure same marks in the ASEE-2010, the selection will be based on their academic record. Written examination will be held in following cities namely Dehradun, Kanpur, Kolkata, and Hardoi (UP). Each candidate must indicate his/her preference for the centre in the application. No TA/DA will be paid to the candidates  to attend the exam under any circumstances. The candidates appearing in the qualifying exam may also apply. The scholarship will be provided to the successful  and eligible candidate after taking admission in the GCBMS Dehradun.
Scheme of Examination Top There would be 100 objective questions in paper carrying 2 marks each. All questions have 4 answers (A, B, C & D), in which one would be most correct. Candidate is expected to choose the most correct/ best suitable answer.
Scoring and Negative Marking Top There is a negative marking of ¼ (for each wrong answer 0.5 marks will be deducted from overall scoring).
Eligibility Top M.Sc. Biotechnology B.Sc. Biotech/CBZ or equivalent with >=55% marks M.Sc. Pharmaceutical Chemistry B.Sc. CBZ/ PCM or equivalent with >=50% marks M.Sc. Microbiology B.Sc. Microbiology/CBZ or equivalent with >=50% marks B.Sc. Biotechnology (with CBZ) 10+2 with PCB with >=45% marks in aggregate
M.Sc. Microbiology Syllabus Top 1. Diversity of Living World (5 Questions) Taxonomic aids, keys, specimen management; Systematics & binomial system of nomenclature; Classification of living organisms (5 kingdom system, major  groups and principles of classification within each group); General description & Salient features of Monerans, Protists, Fungi, Plants and Animals (with major groups). 2. Biochemistry (8 Questions) Entropy, Enthalpy; Gibb’s free energy concept; Laws of thermodynamics; Acids & bases; pH & buffers; Structure, function & metabolism of carbohydrates,  proteins, lipids and nucleic acids; Enzymology: Classification and nomenclature of enzymes; Structure, Mechanism of action, single substrate and bi-substrate  enzymes; Activators and inhibitors of enzymes; Factors affecting the activity of enzymes. 3. Plant Physiology (8 Questions) Minerals required by plant, their absorbable form, functions, deficiency symptoms, essentiality of minerals, N2 metabolism, biological N2 fixation; Cellular  Metabolism: Gluconeogenesis, Glycogenesis and glycogenolysis, hormonal regulation; Oxidation of food, respiratory efficiency of various food components;  transport and detoxification of ammonia, Lipid Metabolism; Photosynthesis: Basic principles of light absorption, excitation energy transfer, electron transports, cycles (C2, C3, C4 & CAM), plant productivity, measurement of photosynthetic parameters; Physiological responses to abiotic stresses; Sensory  photobiology; Physiological affects and mechanism of action of plant growth hormones. 4. Human Biology (8 Questions) General Morphology & Anatomy; Physiology: Control and Disorders of Digestion, Respiration, Body fluids and Circulation, Homoeostasis, Excretion & Urea cycle, Skeleton system & muscle contraction, Nervous system; Immunobiology. 5. Classical Genetics (8 Questions) Principles of Inheritance and Variation: Mendelian genetics, Post Mendelian inheritance; chromosomal theory of inheritance; Linkage, recombination & crossing over; recombination frequency, linkage map; Mutation: General properties of mutations; molecular basis of gene mutation: biochemical basis of gene  mutation DNA repair mechanisms. Pedigree analysis; Human karyotype-banding; genetic and environmental basis of sex determination, Y- and X-linked  genes, Numerical and Structural abnormalities of human chromosomes and related syndromes: Human metabolic disorders; Maternal inheritance; Molecular  Basis of Inheritance: Chemical nature of DNA and RNA; Biological functions of nucleic acids; Search for genetic material, RNA world; Replication; Transcription and processing of RNA, Genetic code; Translation, posttranslational modification; Ribosomes; Regulation of Gene expression. 6. Cell & Molecular Biology (10 Questions) History of cell biology; Microscopy; Staining technique; Centrifugation; Radio-labeling techniques (RIA); Immuno-blotting; ELISA; Study of cytoplasm &  plasma membrane; Structure & Function of Cell-organelles; Genes & Genome; C-value paradox; DNA packaging: Nucleosome model; DNA super-coiling;  DNA Replication, recombination & repair; Transcription & RNA splicing; Translation of protein & gene regulation. 7. Modern Genetics (10 Questions) Gel Electrophoresis (Agarose/ PAGE/ SDS-PAGE/ Pulse-Field GE); Southern blotting, Northern blotting & Western Blotting; DNA Fingerprinting; Gene  mapping; Chromosome banding; Genetics in modern agriculture, animal breeding, medicine, human behavior; Genetic Counseling; Gene therapy; HGP; Gene  Activity in prokaryotes and eukaryotes; Signals for gene control – Hormones and growth factors; Bacterial transformation, transduction and conjugation,  Bacterial chromosome; Bacteriophages: Types, structure and morphology. 8. Evolutionary Biology (8 Questions) Cosmic evolution – Physical basis of life; Theories of origin of life; Origin of life through biochemical evolution; Experimental evidences for origin of life;  Evolution of the prokaryotic & eukaryotic cell; Direct & indirect evidences of evolution (specially study of fossils); Theories of organic evolution- Lamarckism  & Darwinism; Speciation & variation; Origin and evolution of horse & man; Population Genetics; Genetic variations; Polymorphism; Gene  frequency; Hardy Weinberg equilibrium; Genetic drift, Founder effect; Adaptive radiation; ecological significance of molecular variations. 9. Ecology (10 Questions) Ecology: definition, study, branches; Concept of ecosystem; Organism and its environment, distribution of biomes, major physical factors and the  physiological responses shown by organisms; Physical adaptation of plants and animals, rules governing adaptations; Population attributes and growth, logistic  curves, Darwinian fitness; Population interactions and their theories; Ecosystem structure and functions, ecosystem productivity and standing crop, decomposition in nature, energy flow in ecosystem, ecological pyramids, succession of community; Biogeochemical cycles; Biodiversity types and its patterns, importance of diversity, its loss and their causes, conservation strategies ; Environmental issues : Types of pollution, their indicators, causes, effects, prevention and treatment ; Deforestation, recommended forestation, reforestation, case, Chipko Movement; Ozone layer depletion; Global warming; Green house effect. 10. Biostatistics (5 Questions) General mathematical ability, Measures of central tendency (mean median & mode), standard deviation, variance & standard error, chi-square test. 11. Biology and Human Welfare (10 Questions) Health and disease; types of diseases, common diseases in humans; Immunology – Innate and Acquired immunity; Passive and active immunization;  Organization and structure of lymphoid organ; Cells of the immune system; Nature of immune response; Structure and Functions of antibodies: Antigen-Antibody interactions; Humoral immune response; Cell mediated immunity; Auto-immunity; Allergies; Immunodeficiency disorders; etiology of HIV; types, genetics and biochemistry of cancer; Animal husbandry, management of farm animals, breeding strategies (natural and artificial) and their types, economic importance of each; Plant breeding, method of release of new variety, Single cell protein; Tissue culture technique, somatic hybridization; Microbes in Human Welfare: Technology associated and use of Microbes in household, industries, medicine, bio-active molecules, sewage treatment and sewage treatment plants, biogas production, bio-control agents, biofertilizers. 12. Microbiology & Biotechnology (10 Questions) Microbial Culture technique; microbial tools; Isolation, media preparation, cultivation, staining & preservation of microbes; Application of microbiology in  dairy, agriculture, medicine and environmental engineering; technique of separation and isolation of DNA, RNA & Protein; Cryopreservation; Gene cloning, Restriction enzymes, Isoschizomers & Isocaudomers; Cutting & Joining of Nucleic acids, linkers & adapters; Vectors (plasmid/ viral & phage vectors/  cosmid/ fosmid/ BAC/ YAC/ HAC), types of vectors (cloning & expression vectors/ shuttle vectors), vectors for plants (Ti plasmid & Ri plasmid); genomic  and cDNA libraries; nucleotide sequence comparisons and homologies; RFLP, SNP, VNTR, STR, RAPD; general description, types & application of PCR;  io-reactors, upstream & downstream processing, large scale production; Totipotency & Pleuripotency; stem cell technology; Tissue engineering;  Hybridoma technique: production, detection and applications of monoclonal antibodies; Study of vaccines: mechanism of vaccination; types of vaccines; OPV, Hepa
M.Sc. Biotechnology Syllabus Top 1. Diversity of Living World (5 Questions) Taxonomic aids, keys, specimen management; Systematics & binomial system of nomenclature; Classification of living organisms (5 kingdom system, major  groups and principles of classification within each group); General description & Salient features of Monerans, Protists, Fungi, Plants and Animals (with major groups). 2. Biochemistry (8 Questions) Entropy, Enthalpy; Gibb’s free energy concept; Laws of thermodynamics; Acids & bases; pH & buffers; Structure, function & metabolism of carbohydrates,  proteins, lipids and nucleic acids; Enzymology: Classification and nomenclature of enzymes; Structure, Mechanism of action, single substrate and bi-substrate enzymes; Activators and inhibitors of enzymes; Factors affecting the activity of enzymes. 3. Plant Physiology (8 Questions) Water relations: Properties of water, water in tissues and cells, Transport of water and solutes (food, nutrients, gases): Transport across cell membrane;  soil-plant-atmosphere continuum; Minerals required by plant, their absorbable form, functions, deficiency symptoms, essentiality of minerals, N2 metabolism, biological N2 fixation; Cellular Metabolism: Gluconeogenesis, Glycogenesis and glycogenolysis, hormonal regulation; Oxidation of food, respiratory efficiency of various food components; transport and detoxification of ammonia, Lipid Metabolism; Photosynthesis: Basic principles of light absorption, excitation  energy transfer, electron transports, cycles (C2, C3, C4 & CAM), plant productivity, measurement of photosynthetic parameters; Physiological responses to abiotic stresses; Sensory photobiology; Physiological affects and mechanism of action of plant growth hormones; Photoperiodism and its significance,  ndogenous clock and its regulation, floral induction and development, Vernalization; Plant movements; Seed dormancy. 4. Human Biology (8 Questions) General Morphology & Anatomy; Physiology: Control and Disorders of Digestion, Respiration, Body fluids and Circulation, Homoeostasis, Excretion &  Urea cycle, Skeleton system & muscle contraction, Nervous system; Immunobiology. 5. Classical Genetics (8 Questions) Principles of Inheritance and Variation: Mendelian genetics, Post Mendelian inheritance; chromosomal theory of inheritance; Linkage, recombination &  crossing over; recombination frequency, linkage map; Mutation: General properties of mutations; molecular basis of gene mutation: biochemical basis of gene  mutation DNA repair mechanisms. Pedigree analysis; Human karyotype-banding; genetic and environmental basis of sex determination, Y- and X-linked  genes, Numerical and Structural abnormalities of human chromosomes and related syndromes: Human metabolic disorders; Maternal inheritance; Molecular Basis of Inheritance: Chemical nature of DNA and RNA; Biological functions of nucleic acids; Search for genetic material, RNA world; Replication; Transcription and processing of RNA, Genetic code; Translation, posttranslational modification; Ribosomes; Regulation of Gene expression. 6. Cell & Molecular Biology (10 Questions) History of cell biology; Microscopy; Staining technique; Centrifugation; Radio-labeling techniques (RIA); Immuno-blotting; ELISA; Study of cytoplasm &  plasma membrane; Structure & Function of Cell-organelles; Genes & Genome; C-value paradox; DNA packaging: Nucleosome model; DNA super-coiling;  DNA Replication, recombination & repair; Transcription & RNA splicing; Translation of protein & gene regulation. 7. Modern Genetics (10 Questions) Gel Electrophoresis (Agarose/ PAGE/ SDS-PAGE/ Pulse-Field GE); Southern blotting, Northern blotting & Western Blotting; DNA Fingerprinting; Gene  mapping; Chromosome banding; Genetics in modern agriculture, animal breeding, medicine, human behavior; Genetic Counseling; Gene therapy; HGP; Gene Activity in prokaryotes and eukaryotes; Signals for gene control – Hormones and growth factors; Bacterial transformation, transduction and conjugation, Bacterial chromosome; Bacteriophages: Types, structure and morphology. 8. Evolutionary Biology (8 Questions) Cosmic evolution – Physical basis of life; Theories of origin of life; Origin of life through biochemical evolution; Experimental evidences for origin of life;  Evolution of the prokaryotic & eukaryotic cell; Direct & indirect evidences of evolution (specially study of fossils); Theories of organic evolution- Lamarckism  & Darwinism; Speciation & variation; Origin and evolution of horse & man; Population Genetics; Genetic variations; Polymorphism; Gene frequency; Hardy Weinberg equilibrium; Genetic drift, Founder effect; Adaptive radiation; ecological significance of molecular variations. 9. Ecology (10 Questions) Ecology: definition, study, branches; Concept of ecosystem; Organism and its environment, distribution of biomes, major physical factors and the  physiological responses shown by organisms; Physical adaptation of plants and animals, rules governing adaptations; Population attributes and growth, logistic  urves, Darwinian fitness; Population interactions and their theories; Ecosystem structure and functions, ecosystem productivity and standing crop,  decomposition in nature, energy flow in ecosystem, ecological pyramids, succession of community; Biogeochemical cycles; Biodiversity types and its patterns,  importance of diversity, its loss and their causes, conservation strategies ; Environmental issues : Types of pollution, their indicators, causes, effects,  prevention and treatment ; Deforestation, recommended forestation, reforestation, case, Chipko Movement; Ozone layer depletion; Global warming; Green house effect. 10. Biostatistics (5 Questions) General mathematical ability, Measures of central tendency (mean median & mode), standard deviation, variance & standard error, chi-square test. 11. Biology and Human Welfare (10 Questions) Health and disease; types of diseases, common diseases in humans; Immunology – Innate and Acquired immunity; Passive and active immunization;  Organization and structure of lymphoid organ; Cells of the immune system and their differentiation; Lymphocyte traffic; Nature of immune response; Structure and Functions of antibodies: Antigen- Antibody interactions; Humoral immune response; Cell mediated immunity; Immunological memory; Auto-immunity;  Allergies; HLA system in human: MHC haplotypes; Transplantation types and problems; Immunodeficiency disorders; etiology of HIV; types, genetics and  biochemistry of cancer; Drugs and alcohol abuse, Addiction, drug dependence, ill effects, prevention, its abuse in adolescents and its management; Strategies  for food production and enhancement: Animal husbandry, management of farm animals, breeding strategies (natural and artificial) and their types, economic importance of each; Plant breeding, method of release of new variety, Single cell protein; Tissue culture technique, somatic hybridization; Microbes in Human  Welfare: Technology associated and use of Microbes in household, industries, medicine, bio-active molecules, sewage treatment and sewage treatment  plants, biogas production, bio-control agents, biofertilizers. 12. Biotechnology & Genetic Engineering (10 Questions) Genetic engineering tools & technique; Technique of separation and isolation of DNA, RNA & Protein; Cryopreservation; Gene cloning, restriction enzymes,  soschizomers & isocaudomers; Cutting & joining of nucleic acids, linkers & adapters; Vectors (plasmid/ viral & phage vectors/ cosmid/ fosmid/  phasmid/ BAC/ YAC/ HAC), types of vectors (cloning & expression vectors/ shuttle vectors), vectors for plants
M.Sc. Pharmaceutical Chemistry Syllabus Top 1. Chemistry (50 Questions) [Compulsory for All] Atomic Structure; Periodic table & periodic properties; Chemical bonding; s-block elements; p-block elements; d-block elements & coordination  compounds; chemistry of noble gases; Oxidation & reduction; Organo-metallic compounds Hybridization; Mechanism of organic reaction; Stereochemistry  of organic compounds; Isolation, purification, identification & classification of organic compounds; Isomerism; Hydrocarbons (aliphatic & aromatic);  Alcohols; Phenols; Ethers & Epoxides; Aldehyde & ketones; Carboxylic Acids; Structure & Function of Bio-molecules (Carbohydrate, Proteins & Amino- acids, Nucleic Acids, Vitamins); Organic compounds of Nitrogen. Chemical equilibrium & chemical kinetics; Gaseous state; Liquid state; Solid state; Colloidal system; Catalysts & catalysis; Solution; Distribution law; Thermodynamics; Entropy, Enthalpy; Gibb’s free energy concept; Acids & bases; pH &  buffers; Electrochemistry; Phase equilibrium; Surface Chemistry. 2. Tools & Techniques in Pharmaceutics (10 Questions) [Compulsory for All] Disease Diagnosis techniques (including ELISA & PCR), Centrifugation and ultra centrifugation, gel permeation; Ion exchange chromatography,  electrophoresis, hydrophobic interaction, partition chromatography; Colorimetry, UV-visible spectrophotometry, fluorescence spectroscopy, x-ray  crystallography, radio isotopes techniques; Salt precipitation, precipitation with organic solvent; Microscopy- LM,TEM,SEM; Cell fractionation, cell growth  determination; Chromosomal techniques- Staining , banding pattern, karyotyping; Mutagenic techniques- Bacterial and seed mutagenesis , recombination in bacteria, conjugation, transduction, breeding methods in plants, pedigree analysis, DNA isolation. 3. Biology (30 Questions) [For BIO Group: PCB] Microbial culture tools & techniques; Isolation, media preparation, cultivation, staining & preservation of microbes; Application of microbiology in dairy,  agriculture, medicine and environmental engineering; History of cell biology; Microscopy; Staining technique; Centrifugation; Study of cytoplasm & plasma membrane; Structure & Function of Cell-organelles; Genes & Genome; DNA Replication; Transcription; Translation of protein & gene regulation. Principles of Inheritance and Variation: Mendelian genetics, Post Mendelian inheritance; chromosomal theory of inheritance; Linkage, recombination & crossing over; recombination frequency; Mutation; Numerical and Structural abnormalities of human chromosomes and related syndromes. Chemical nature of DNA and  RNA; Biological functions of nucleic acids; Search for genetic material, RNA world; Replication; Transcription and processing of RNA, Genetic code;  Translation, post-translational modification; Ribosomes; Regulation of Gene expression. Structure, function & metabolism of carbohydrates, proteins, lipids  and nucleic acids; Enzymology: Classification and nomenclature of enzymes; Structure, Mechanism of action, single substrate and bi-substrate enzymes;  Activators and inhibitors of enzymes;  Factors affecting the activity of enzymes.Health and disease; types of diseases, common diseases in humans;  Immunology – Innate and Acquired immunity; Passive and active immunization; Organization and structure of lymphoid organ; Cells of the immune system  and their differentiation; Lymphocyte traffic; Nature of immune response; Structure and Functions of antibodies: Antigen- Antibody interactions; Humoral   immune response; Cell mediated immunity; Immunological memory; Auto-immunity; Allergies; Immunodeficiency disorders; HIV; Cancer; Drugs and alcohol  abuse, Addiction, drug dependence, ill effects, prevention, its abuse in adolescents and its management. DNA Fingerprinting; Genetics in modern agriculture,  animal breeding, medicine, human behavior; Gene therapy; bacterial transformation, transduction and conjugation, Bacterial chromosome; Bacteriophages: Types, structure and morphology. 4. Mathematics & Biostatistics (30 Questions) [For Math Group: PCM] Mensuration (calculation of length, width, height, area, volume etc.); Common algebra; Trigonometry; Mean, median, mode, standard deviation, variation,  standard error; Probability and distribution; Correlation & regression; ANOVA; t-test; Z-test; chi-square test; Integration & Differentiation; Calculus;  Geometry; Equation of Line.
B.Sc. Biotechnology Syllabus Top 1. General Mathematical Calculations (10 Questions) Mensuration (calculation of length, width, height, area, volume etc.); Common algebra; Trigonometry; Time, speed & distance; Geometry; Average,  percentage, profits & loss; Mean, median, mode, standard deviation, variation, standard error & chi-square test. 2. General Mental Ability (3 Questions) 3 questions would be based on general mental ability viz. Simple series completion; Coding-decoding; Analogy. 3. General Awareness (5 Questions): 5 Questions would be based on general awareness regarding science, pollution, population explosion, food crisis, fuel & energy crisis; Current knowledge  concerning the above all. 4. General Chemistry (12 Questions) Chemical equilibrium & chemical kinetics; Solution; Distribution law; Catalysts & catalysis; Colloidal system; Thermodynamics; Isolation, purification,  identification & classification of organic compounds; Isomerism; Reaction Mechanisms of organic compounds; 5. Biology (60 Questions) a. Botany (10 Questions) Questions regarding bacteria, viruses, algae, fungi, bryophytes, pteridophytes, gymnosperms & angiosperms. b. Zoology (10 Questions) Questions regarding protozoa, platyhelminthes, annelida, arthropoda & chordata. c. Genetics (8 Questions) Mendel’s law, mutation, genetic diseases & syndromes, chromosomal basis of inheritance; incomplete dominance. d. Cell & Molecular Biology (8 Questions) Microscopy; Prokaryotic vs. Eukaryotic cell; Study of cell organelles; Nucleus & chromosome; DNA replication, transcription & translation. e. Biochemistry & Immunology (8 Questions) Biomolecules (carbohydrate, protein, lipid, nucleic acids, vitamins, hormones etc.), pH & buffer, acid & bases; enzymes; Glycolysis & Kreb’s cycle; Health and disease; types of diseases, common diseases in humans; Immunology – Innate and Acquired immunity; Passive and active immunization. f. Ecology, Evolution & Environment (8 Questions) Theories of origin of life; Origin of life through biochemical evolution; Experimental evidences for origin of life; Direct & indirect evidences of evolution  (specially study of fossils); Theories of organic evolution- Lamarckism & Darwinism; Speciation & variation; Origin and evolution of horse & man; Ecology: definition, study, branches; Concept of ecosystem; Organism and its environment; Adaptation of plants and animals, rules governing adaptations; Darwinism; Ecosystem structure and functions, ecosystem productivity and standing crop, decomposition in nature, energy flow in ecosystem, ecological pyramids, succession of community; Biogeochemical cycles; Biological conservation strategies; Environmental issues : Types of pollution, their indicators, causes, effects, prevention and treatment ; Deforestation & reforestation; Chipko Movement; Ozone layer depletion; Global warming; Green house effect. g. Applied Biology (8 Questions) Use of microbes, plants & animals for human beings. 6. Introductory Biotechnology (10 Questions) Genetic engineering tools & technique; Technique of separation and isolation of DNA, RNA & Protein; Cryopreservation; Gene cloning, restriction enzymes;  Cutting & joining of nucleic acids; Vectors (plasmid/ viral & phage vectors), vectors for plants (Ti plasmid & Ri plasmid); Bio-reactors, upstream & downstream processing, large scale production; Totipotency & pleuripotency; Stem cell technology; Tissue engineering; Vaccination: mechanism of  vaccination; types of vaccines; OPV, Hepatitis-B vaccine; Biotechnological products.
Courses Top M.Sc. Biotechnology M.Sc. Pharmaceutical Chemistry M.Sc. Microbiology B.Sc. Biotechnology (with CBZ)

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