BIT - Birla Institute of Technology - Online Entrance Test for M.Sc. |
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(40 questions - objective type)
Systems of classification (non-phylogenetic vs. phylogenetic - outline): Bacteria, Archea, Eukaryotic microbes plants and animals
Theory and practice of sterilization: Principles of microbial nutrition; Culture techniques for isolation of microorganisms; Light and phase contrast microscopy
Definition of growth: Growth curve; role of microorganisms in transformation of organic matter and in the causation of diseases
Structure and function of biomolecules: Amino acids, Carbohydrates, Lipids, Proteins and Nucleic acids. Bacterial genetic system: transformation, conjugation, transduction, recombination, plasmids, transposons;
DNA replication: Transcription and translation. Biochemical regulation of gene expression, Recombinant DNA technology and applications: PCR, DNA-microarray. Prokaryotic and eukaryotic genome organization, regulation of gene expression, gene mutation and repair, chromosomal aberrations (numerical and structural), transposons
Metabolism and bioenergetics: Metabolic pathways and their regulation: glycolysis, TCA cycle, pentose phosphate pathway, oxidative phosphorylation, gluconeogenesis, glycogen and fatty acid metabolism. Metabolism of Nitrogen containing compounds: nitrogen fixation, amino acids and nucleotides. Photosynthesis: the Calvin cycle
Cell structure, organization: organelles, cytoskeleton, cell wall and membranes; anatomy of root, stem and leaves, meristems, vascular system, their ontogeny, structure and functions, secondary growth in plants and stellar organization. Cell cycle, life cycle of an angiosperm, pollination, fertilization, embryogenesis, seed formation, seed storage proteins, seed dormancy and germination
Principles, methods of selection, hybridization, heterosis: male sterility, genetic maps and molecular markers, sporophytic and gametophytic self incompability, haploidy, triploidy, somatic cell hybridization, marker-assisted selection, gene transfer methods viz. direct and vector-mediated, plastid transformation, transgenic plants and their application in agriculture
General account of economically and medicinally important plants: cereals, pulses, plants yielding fibers, timber, sugar, beverages, oils, rubber, pigments, dyes, gums, drugs and narcotics. Economic importance of algae, fungi, lichen and bacteria
Nature and classification of plant diseases: diseases of important crops caused by fungi, bacteria and viruses, and their control measures, mechanism(s) of pathogenesis and resistance, molecular detection of pathogens; plant-microbe beneficial interactions
Comparative physiology: the respiratory system, circulatory system, digestive system, the nervous system, the excretory system, the endocrine system, the reproductive system, the skeletal system, osmoregulation
Animal cell metabolism and regulation: cell cycle; primary cell culture; nutritional requirements for animal cell culture; application of animal cell culture for production of vaccines, growth hormones; interferons, cytokines and therapeutic proteins; stem cells and its application in organ synthesis; gene therapy; transgenic animals
Immunology: the immune response, cellular and humoral immune response, evolution of the immune system, Active and passive immunity. Antibody structure, function, Cells of the immune system; T, B and macrophages
Embryonic development: cellular differentiation, organogenesis, metamorphosis, genetic basis of development. Types of behaviours, courtship, mating and territoriality, instinct, learning and memory, social behaviour across the animal taxa, communication, pheromones, evolution of animal behaviour
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